Research tools

Quality documentation

How to read a Certificate of Analysis

A practical checklist for reviewing research-material documentation. A COA supports traceability; it is not a substitute for independent verification or laboratory quality controls.

1. Confirm identity

Check that the product name, batch or lot number, and sample description match the material you received.

2. Check the analytical methods

Look for the test method used, such as HPLC for chromatographic purity or mass spectrometry for identity confirmation. A result without a method is difficult to interpret.

3. Read purity in context

Purity is method-specific. Review the reported percentage alongside the method, detection limits, and any listed related substances or impurities.

4. Review dates and sign-off

Check the testing date, report date, laboratory details, and authorisation or quality approval fields.

5. Keep the full document

Retain the original PDF with purchase, batch, storage, and laboratory records so assay data remain traceable.

Research-use notice: Product documentation and this guide are provided for laboratory research context only. Follow your institution’s approved procedures and consult qualified analytical personnel when interpreting assay data.